Stabilized porous liposomes with encapsulated Gd-labeled dextran as a highly efficient MRI contrast agent†
Abstract
A highly efficient contrast agent for magnetic resonance imaging was developed by encapsulating gadolinium within a stabilized porous liposome. The highly porous membrane leads to a high relaxivity of the encapsulated Gd. The stability of the liposome was improved by forming a polymer network within the bilayer membrane.