Issue 27, 2014
From the journal:

Chemical Communications

Spatially marking and quantitatively counting membrane immunoglobulin M in live cells via Ag cluster–aptamer probes†

Ru Liu,a   Jiao Zhai,a   Li Liu,a   Yaling Wang,a   Yueteng Wei,a   Xinglu Jiang,a   Liang Gao,a   Huarui Zhu,a   Yuliang Zhao,a   Zhifang Chaia  and  Xueyun Gao*a  

* Corresponding authors

a CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, P. R. China
E-mail: gaoxy@ihep.ac.cn
Fax: +86-10-88236456
Tel: +86-10-88236709

Abstract

A probe composed of an aptamer and a silver cluster, where the aptamer targets mIgM of live cells and the silver cluster provides fluorescent imaging and mass quantification of mIgM of live cells, is presented. This new probe simultaneously provides accurate spatial and mass information of mIgM in live cells.

Graphical abstract: Spatially marking and quantitatively counting membrane immunoglobulin M in live cells via Ag cluster–aptamer probes

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Article information

DOI
https://doi.org/10.1039/C3CC49036J
Article type
Communication
Submitted
27 Nov 2013
Accepted
13 Jan 2014
First published
13 Jan 2014

Chem. Commun., 2014,50, 3560-3563

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Spatially marking and quantitatively counting membrane immunoglobulin M in live cells via Ag cluster–aptamer probes

R. Liu, J. Zhai, L. Liu, Y. Wang, Y. Wei, X. Jiang, L. Gao, H. Zhu, Y. Zhao, Z. Chai and X. Gao, Chem. Commun., 2014, 50, 3560 DOI: 10.1039/C3CC49036J

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