Issue 48, 2014

Boronic acid ester with dopamine as a tool for bioconjugation and for visualization of cell apoptosis

Abstract

Boronic esters are investigated as a pathway to conjugate biological molecules to polymers. Although the stability of the boronic ester was slightly dependent on the molecular weight of the polymer and the pH value, the conjugates were stable when micelles were endocytosed by cells. Only the onset of apoptosis led to cleavage of the boronic ester.

Graphical abstract: Boronic acid ester with dopamine as a tool for bioconjugation and for visualization of cell apoptosis

Supplementary files

Article information

Article type
Communication
Submitted
29 Nov 2013
Accepted
14 Apr 2014
First published
14 Apr 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 6390-6393

Author version available

Boronic acid ester with dopamine as a tool for bioconjugation and for visualization of cell apoptosis

W. Scarano, H. Lu and M. H. Stenzel, Chem. Commun., 2014, 50, 6390 DOI: 10.1039/C3CC49100E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements