Issue 30, 2014
From the journal:

Chemical Communications

Expanding the genetic code for site-specific labelling of tobacco mosaic virus coat protein and building biotin-functionalized virus-like particles†

F. C. Wu,‡abc   H. Zhang,‡d   Q. Zhou,ab   M. Wu,a   Z. Ballard,c   Y. Tian,a   J. Y. Wang,*d   Z. W. Niu*a  and  Y. Huanga  

* Corresponding authors

a Technical Institute of Physics and Chemistry, CAS, Beijing 100190, China
E-mail: niu@mail.ipc.ac.cn

b University of Chinese Academy of Sciences, Beijing 100080, China

c Max Planck Institute for the Science of Light, Erlangen, Germany

d National Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
E-mail: jwang@ibp.ac.cn

Abstract

A method for site-specific and high yield modification of tobacco mosaic virus coat protein (TMVCP) utilizing a genetic code expanding technology and copper free cycloaddition reaction has been established, and biotin-functionalized virus-like particles were built by the self-assembly of the protein monomers.

Graphical abstract: Expanding the genetic code for site-specific labelling of tobacco mosaic virus coat protein and building biotin-functionalized virus-like particles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC49137D
Article type
Communication
Submitted
01 Dec 2013
Accepted
17 Feb 2014
First published
19 Feb 2014

Chem. Commun., 2014,50, 4007-4009

Author version available

Download author version (PDF)

Permissions

Request permissions

Expanding the genetic code for site-specific labelling of tobacco mosaic virus coat protein and building biotin-functionalized virus-like particles

F. C. Wu, H. Zhang, Q. Zhou, M. Wu, Z. Ballard, Y. Tian, J. Y. Wang, Z. W. Niu and Y. Huang, Chem. Commun., 2014, 50, 4007 DOI: 10.1039/C3CC49137D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements