Issue 23, 2014
From the journal:

Chemical Communications

Silver-catalyzed one-pot cyclization/fluorination of 2-alkynylanilines: highly efficient synthesis of structurally diverse fluorinated indole derivatives†

Lei Yang,a   Yuanhong Ma,a   Feijie Song*a  and  Jingsong You*a  

* Corresponding authors

a Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, and State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, 29 Wangjiang Road, Chengdu 610064, PR China
E-mail: fsong@scu.edu.cn, jsyou@scu.edu.cn
Fax: +86-28-85412203

Abstract

Highly efficient approaches to obtain structurally diverse fluorinated indole derivatives have been realized through the Ag-catalyzed one-pot cyclization/fluorination of 2-alkynylanilines in the presence of NFSI or Selectfluor.

Graphical abstract: Silver-catalyzed one-pot cyclization/fluorination of 2-alkynylanilines: highly efficient synthesis of structurally diverse fluorinated indole derivatives

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Article information

DOI
https://doi.org/10.1039/C3CC49851D
Article type
Communication
Submitted
30 Dec 2013
Accepted
28 Jan 2014
First published
28 Jan 2014

Chem. Commun., 2014,50, 3024-3026

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Silver-catalyzed one-pot cyclization/fluorination of 2-alkynylanilines: highly efficient synthesis of structurally diverse fluorinated indole derivatives

L. Yang, Y. Ma, F. Song and J. You, Chem. Commun., 2014, 50, 3024 DOI: 10.1039/C3CC49851D

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