By splitting the catalytic core of DNAzymes into two halves, two Pb2+-specific DNAzymes retain partial activity, while they show opposite trends of activity as a function of the split site, revealing important nucleotides for catalysis and metal binding.
P. J. Huang and J. Liu, Chem. Commun., 2014, 50, 4442 DOI: 10.1039/C4CC00864B
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