Issue 54, 2014
From the journal:

Chemical Communications

A near-infrared-emitting fluorescent probe for monitoring mitochondrial pH†

Ping Li,a   Haibin Xiao,a   Yinfang Cheng,a   Wen Zhang,a   Fang Huang,a   Wei Zhang,a   Hui Wanga  and  Bo Tang*a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn
Tel: +86 531-8618-0017

Abstract

We demonstrate a new small molecule fluorescent probe, possessing near-infrared (NIR) emission and an unusually large Stokes shift. It can be readily taken up by live cells and mitochondria, and track subtle pH changes with effectively reduced biological background fluorescence and improved measurement accuracy.

Graphical abstract: A near-infrared-emitting fluorescent probe for monitoring mitochondrial pH

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Article information

DOI
https://doi.org/10.1039/C4CC01390E
Article type
Communication
Submitted
23 Feb 2014
Accepted
09 May 2014
First published
15 May 2014

Chem. Commun., 2014,50, 7184-7187

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A near-infrared-emitting fluorescent probe for monitoring mitochondrial pH

P. Li, H. Xiao, Y. Cheng, W. Zhang, F. Huang, W. Zhang, H. Wang and B. Tang, Chem. Commun., 2014, 50, 7184 DOI: 10.1039/C4CC01390E

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