The Michael addition of 3-substituted oxindoles to nitroolefins was catalyzed by a novel tartrate-derived guanidine in high yield with excellent diastereo- and enantioselectivity. This method showed an extraordinarily broad substrate scope in terms of both reaction partners.
L. Zou, X. Bao, Y. Ma, Y. Song, J. Qu and B. Wang, Chem. Commun., 2014, 50, 5760 DOI: 10.1039/C4CC01817F
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