Pyridyl-cyclodextrin for ultra-hydrosolubilization of [60]fullerene

Abstract

An efficient hydrosolubilizing reagent for [60]fullerene (C₆₀) was newly developed with a γ-cyclodextrin (γ-CD) derivative having triazole-methoxypyridyl moieties at its 6-hydroxyl positions (PCD). Through solid-state mechanochemical complexation, PCD forms a hydrosoluble inclusion complex of C₆₀ with a concentration of more than 70 mM. This is approximately 90 times greater than that with non-substituted γ-CD prepared by the same method.