Issue 49, 2014

Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C–H bonds

Abstract

A novel metal-free synthesis of quinazolinones via dual amination of sp3 C–H bonds was developed. The sp3 carbon in methylarenes or adjacent to a heteroatom in DMSO, DMF or DMA was used as the one carbon synthon.

Graphical abstract: Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C–H bonds

Supplementary files

Article information

Article type
Communication
Submitted
10 Apr 2014
Accepted
02 May 2014
First published
02 May 2014

Chem. Commun., 2014,50, 6471-6474

Author version available

Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C–H bonds

D. Zhao, T. Wang and J. Li, Chem. Commun., 2014, 50, 6471 DOI: 10.1039/C4CC02648A

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