Microwave-assisted phosphitylation of sterically hindered nucleosides is demonstrated to be an efficient method for the preparation of corresponding phosphoramidites (otherwise onerous under standard conditions) and is shown to be general in its applicability.
G. Meher, T. Efthymiou, M. Stoop and R. Krishnamurthy, Chem. Commun., 2014, 50, 7463 DOI: 10.1039/C4CC03092C
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