Randomly arrayed G-quadruplexes can serve as an efficient peroxidase-mimic DNAzyme and provide a novel and facile method to detect terminal deoxynucleotidyl transferase (TdT). Moreover, this G-rich sequence binding to the thioflavin T (ThT) dye can be applied in real-time fluorescent detection of TdT activity.
Z. Liu, W. Li, Z. Nie, F. Peng, Y. Huang and S. Yao, Chem. Commun., 2014, 50, 6875 DOI: 10.1039/C4CC03103B
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