Cyclodextrin-based supramolecular nanoparticles stabilized by balancing attractive host–guest and repulsive electrostatic interactions

Abstract

Multicomponent, negatively charged supramolecular nanoparticles (SNPs) were formed by multivalent host–guest interactions without the need of a stopper in water and in PBS. Their size and stability are controlled owing to a balance of forces between attractive supramolecular and repulsive electrostatic interactions.