Issue 76, 2014
From the journal:

Chemical Communications

Programmed stereoselective assembly of DNA-binding helical metallopeptides†

Ilaria Gamba,a   Gustavo Rama,a   Elizabeth Ortega-Carrasco,b   Jean-Didier Maréchal,b   José Martínez-Costas,c   M. Eugenio Vázquez*d  and  Miguel Vázquez López*a  

* Corresponding authors

a Departamento de Química Inorgánica, Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain
E-mail: miguel.vazquez.lopez@usc.es

b Departament de Química, Universitat Autònoma de Barcelona, 08193 Cerdanyola, Spain

c Departamento de Bioquímica y Biología Molecular, Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain

d Departamento de Química Orgánica, Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain
E-mail: eugenio.vazquez@usc.es

Abstract

A flexible and versatile synthetic approach for the construction of water-stable DNA-binding chiral peptide helicates based on the solid phase peptide synthesis (SPPS) methodology is reported.

Graphical abstract: Programmed stereoselective assembly of DNA-binding helical metallopeptides

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Article information

DOI
https://doi.org/10.1039/C4CC03606A
Article type
Communication
Submitted
13 May 2014
Accepted
04 Jul 2014
First published
07 Jul 2014

Chem. Commun., 2014,50, 11097-11100

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Programmed stereoselective assembly of DNA-binding helical metallopeptides

I. Gamba, G. Rama, E. Ortega-Carrasco, J. Maréchal, J. Martínez-Costas, M. Eugenio Vázquez and M. V. López, Chem. Commun., 2014, 50, 11097 DOI: 10.1039/C4CC03606A

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