Issue 66, 2014
From the journal:

Chemical Communications

A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification†

Sujuan Ye,ab   Yanying Wu,b   Wen Zhang,a   Na Lia  and  Bo Tang*a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn
Fax: +86-531-86180017

b College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China

Abstract

A novel surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification, achieving high sensitivity, universality, rapid analysis, and high selectivity.

Graphical abstract: A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification

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Article information

DOI
https://doi.org/10.1039/C4CC03988B
Article type
Communication
Submitted
25 May 2014
Accepted
01 Jul 2014
First published
01 Jul 2014

Chem. Commun., 2014,50, 9409-9412

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A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification

S. Ye, Y. Wu, W. Zhang, N. Li and B. Tang, Chem. Commun., 2014, 50, 9409 DOI: 10.1039/C4CC03988B

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