Issue 70, 2014
From the journal:

Chemical Communications

Gold-plated magnetic polymers for highly specific enrichment and label-free detection of blood biomarkers under physiological conditions†

Seung-Ryong Kwon,a   Chang Su Jeon,a   Nam Young Hong,b   Kwang Pyo Kim,*b   Inseong Hwang*a  and  Taek Dong Chung*a  

* Corresponding authors

a Department of Chemistry, Seoul National University, Seoul 151-747, Korea
E-mail: inseong@snu.ac.kr, tdchung@snu.ac.kr

b Department of Applied Chemistry, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 446-701, Korea
E-mail: kimkp@khu.ac.kr

Abstract

A mass-based label-free detection of blood biomarkers under physiological conditions is realised using gold-plated magnetic polymer microspheres covered with self-assembled monolayers of polyethylene glycol alkanethiolates that effectively prevent heavy nonspecific binding of serum proteins.

Graphical abstract: Gold-plated magnetic polymers for highly specific enrichment and label-free detection of blood biomarkers under physiological conditions

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Article information

DOI
https://doi.org/10.1039/C4CC04281F
Article type
Communication
Submitted
04 Jun 2014
Accepted
09 Jul 2014
First published
09 Jul 2014

Chem. Commun., 2014,50, 10066-10069

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Gold-plated magnetic polymers for highly specific enrichment and label-free detection of blood biomarkers under physiological conditions

S. Kwon, C. S. Jeon, N. Y. Hong, K. P. Kim, I. Hwang and T. D. Chung, Chem. Commun., 2014, 50, 10066 DOI: 10.1039/C4CC04281F

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