Issue 77, 2014

Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens

Abstract

Red-shifted fluorescent indicators for magnesium were developed by incorporation of sulfur or selenium in the azole moiety of ‘fura’ fluorophores. Single atom replacement in the acceptor of these ITC probes affords longer excitation and emission wavelengths as well as greater separation between excitation bands, valuable for ratiometric intracellular Mg2+ imaging.

Graphical abstract: Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens

Supplementary files

Article information

Article type
Communication
Submitted
12 Jun 2014
Accepted
23 Jul 2014
First published
05 Aug 2014

Chem. Commun., 2014,50, 11358-11361

Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens

M. S. Afzal, J. Pitteloud and D. Buccella, Chem. Commun., 2014, 50, 11358 DOI: 10.1039/C4CC04460F

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