A copper-catalyzed Markovnikov-type intermolecular azidocyanation of aryl alkenes has been developed to give a series of α-azido-propanenitriles in moderate to good yields. This method may provide a potential strategy for the synthesis of corresponding 3-amino-2-arylpropanoic acid.
L. Xu, X. Mou, Z. Chen and S. Wang, Chem. Commun., 2014, 50, 10676 DOI: 10.1039/C4CC04640D
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