Issue 79, 2014
From the journal:

Chemical Communications

Enzymatic size control of RNA particles using complementary rolling circle transcription (cRCT) method for efficient siRNA production†

Daehoon Han,a   Yongkuk Park,a   Hyangsu Nama  and  Jong Bum Lee*a  

* Corresponding authors

a Department of Chemical Engineering, University of Seoul, Seoul, South Korea
E-mail: jblee@uos.ac.kr
Fax: +82 26490 2364
Tel: +82 26490 2372

Abstract

A novel fabrication method for RNA particles (RPs) was developed based on enzymatic polymerization, and the size of the RPs was controlled intentionally by adjusting the RNA polymerase concentration for a variety of potential applications.

Graphical abstract: Enzymatic size control of RNA particles using complementary rolling circle transcription (cRCT) method for efficient siRNA production

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Article information

DOI
https://doi.org/10.1039/C4CC04969A
Article type
Communication
Submitted
29 Jun 2014
Accepted
07 Aug 2014
First published
07 Aug 2014

Chem. Commun., 2014,50, 11665-11667

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Enzymatic size control of RNA particles using complementary rolling circle transcription (cRCT) method for efficient siRNA production

D. Han, Y. Park, H. Nam and J. B. Lee, Chem. Commun., 2014, 50, 11665 DOI: 10.1039/C4CC04969A

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