Metal chelators masked with protecting groups for targeted release have the potential to conditionally modulate cellular metals. We report a new route to prepare cis-cinnamate protecting groups that enabled development of a prochelator with chemical stimulus response, fluorescent reporting and active compound release in a single structure.
A. T. Franks and K. J. Franz, Chem. Commun., 2014, 50, 11317 DOI: 10.1039/C4CC05076B
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