Issue 86, 2014
From the journal:

Chemical Communications

Sensitive quantification of messenger RNA with a real-time ligase chain reaction by using a ribonucleotide-modified DNA probe†

Yanlei Hu,a   Hongxia Jia,a   Yucong Wang,a   Yongqiang Chenga  and  Zhengping Li*a  

* Corresponding authors

a Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, Hebei Province, P. R. China
E-mail: lzpbd@snnu.edu.cn
Fax: +86 29 81530859

Abstract

A highly sensitive and specific assay is developed for quantification of messenger RNA with a real-time fluorescence ligase chain reaction by using a ribonucleotide-modified DNA probe.

Graphical abstract: Sensitive quantification of messenger RNA with a real-time ligase chain reaction by using a ribonucleotide-modified DNA probe

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Article information

DOI
https://doi.org/10.1039/C4CC05102E
Article type
Communication
Submitted
03 Jul 2014
Accepted
03 Sep 2014
First published
03 Sep 2014

Chem. Commun., 2014,50, 13093-13095

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Sensitive quantification of messenger RNA with a real-time ligase chain reaction by using a ribonucleotide-modified DNA probe

Y. Hu, H. Jia, Y. Wang, Y. Cheng and Z. Li, Chem. Commun., 2014, 50, 13093 DOI: 10.1039/C4CC05102E

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