Self-assembled phospholipid vesicles are functionalized with thrombin-binding aptamers using a thiol-click reaction. The resulting aptasensors signal the binding of the analyte to the vesicle surface by changes of the emission properties of membrane co-embedded reporter dyes.
A. Müller and B. König, Chem. Commun., 2014, 50, 12665 DOI: 10.1039/C4CC05221H
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