Issue 80, 2014

A highly selective fluorescent probe for hypochlorite and its endogenous imaging in living cells

Abstract

An oxime based fluorescent probe has been designed and synthesized, which detects free as well as enzymatically generated hypochlorite with a low detection limit and high sensitivity. In addition, the probe was successfully utilized for the monitoring of endogenously produced hypochlorite in LPS stimulated cell lines, C6 glioma and BV2 microglia.

Graphical abstract: A highly selective fluorescent probe for hypochlorite and its endogenous imaging in living cells

Supplementary files

Article information

Article type
Communication
Submitted
11 Jul 2014
Accepted
16 Aug 2014
First published
18 Aug 2014

Chem. Commun., 2014,50, 11911-11914

Author version available

A highly selective fluorescent probe for hypochlorite and its endogenous imaging in living cells

S. I. Reja, V. Bhalla, A. Sharma, G. Kaur and M. Kumar, Chem. Commun., 2014, 50, 11911 DOI: 10.1039/C4CC05356G

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