Issue 95, 2014
From the journal:

Chemical Communications

Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery†

Yue Lu,ab   Ran Mo,ab   Wanyi Tai,ab   Wujin Sun,ab   Dennis B. Pacardo,ab   Chenggen Qian,abc   Qundong Shen,c   Frances S. Liglera  and  Zhen Gu*ab  

* Corresponding authors

a Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, USA
E-mail: zgu@email.unc.edu, zgu3@ncsu.edu

b Center for Nanotechnology in Drug Delivery and Division of Molecular Pharmaceutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

c Department of Polymer Science & Engineering, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, China

Abstract

Self-folded redox/acid dual-responsive nanocarriers (RAD-NCs) are developed for physiologically triggered delivery of anticancer drugs. The evidenced redox/acid responsiveness, facile decoration of ligands, and active tumor-targeting capability of RAD-NCs suggest their potential as a promising formulation for tumor-targeted chemotherapy.

Graphical abstract: Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4CC07004F
Article type
Communication
Submitted
05 Sep 2014
Accepted
09 Oct 2014
First published
21 Oct 2014

Chem. Commun., 2014,50, 15105-15108

Permissions

Request permissions

Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery

Y. Lu, R. Mo, W. Tai, W. Sun, D. B. Pacardo, C. Qian, Q. Shen, F. S. Ligler and Z. Gu, Chem. Commun., 2014, 50, 15105 DOI: 10.1039/C4CC07004F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements