Issue 95, 2014

A novel aggregation-induced emission based fluorescent probe for an angiotensin converting enzyme (ACE) assay and inhibitor screening

Abstract

A ‘turn-on’ fluorescent probe based on aggregation-induced emission (AIE) has been developed. It exhibits excellent selectivity and sensitivity for monitoring angiotensin converting enzyme (ACE) activity both in solutions and in living cells as well as for screening ACE inhibitors in vitro.

Graphical abstract: A novel aggregation-induced emission based fluorescent probe for an angiotensin converting enzyme (ACE) assay and inhibitor screening

Supplementary files

Article information

Article type
Communication
Submitted
11 Sep 2014
Accepted
06 Oct 2014
First published
06 Oct 2014

Chem. Commun., 2014,50, 15075-15078

Author version available

A novel aggregation-induced emission based fluorescent probe for an angiotensin converting enzyme (ACE) assay and inhibitor screening

H. Wang, Y. Huang, X. Zhao, W. Gong, Y. Wang and Y. Cheng, Chem. Commun., 2014, 50, 15075 DOI: 10.1039/C4CC07161A

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