Issue 99, 2014
From the journal:

Chemical Communications

Gold nanoparticles functionalized with cresyl violet and porphyrin via hyaluronic acid for targeted cell imaging and phototherapy†

Yanchao Song,ab   Zhe Wang,a   Lihong Li,a   Wen Shi,a   Xiaohua Lia  and  Huimin Ma*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
E-mail: mahm@iccas.ac.cn

b Key Laboratory of Radiological Protection and Nuclear Emergency, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China

Abstract

Gold nanoparticles are functionalized as a nanoprobe with cresyl violet and porphyrin via hyaluronic acid. The nanoprobe becomes highly fluorescent in the presence of hyaluronidase or under ultraviolet irradiation, and can be used to target cancer cells via the overexpressed CD44 receptor for fluorescence imaging and phototherapy.

Graphical abstract: Gold nanoparticles functionalized with cresyl violet and porphyrin via hyaluronic acid for targeted cell imaging and phototherapy

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Article information

DOI
https://doi.org/10.1039/C4CC07565J
Article type
Communication
Submitted
25 Sep 2014
Accepted
24 Oct 2014
First published
24 Oct 2014

Chem. Commun., 2014,50, 15696-15698

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Gold nanoparticles functionalized with cresyl violet and porphyrin via hyaluronic acid for targeted cell imaging and phototherapy

Y. Song, Z. Wang, L. Li, W. Shi, X. Li and H. Ma, Chem. Commun., 2014, 50, 15696 DOI: 10.1039/C4CC07565J

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