Issue 5, 2014
From the journal:

Chemical Society Reviews

“Smart” DNA interfaces

Vinalia Tjong,a   Lei Tang,b   Stefan Zauscher*bc  and  Ashutosh Chilkoti*ac  

* Corresponding authors

a Department of Biomedical Engineering, Duke University, Box 90281, Durham, North Carolina 27708, USA
E-mail: chilkoti@duke.edu
Fax: +1 919-660-5409
Tel: +1 919-660-5373

b Department of Mechanical Engineering and Materials Science, Duke University, 144 Hudson Hall Box 90300, Durham, North Carolina 27708, USA
E-mail: zauscher@duke.edu
Fax: +1 919-660-8963
Tel: +1 919-660-5360

c Center for Biologically Inspired Materials and Materials Systems, Duke University, Durham, North Carolina 27708, USA

Abstract

This review focuses on surface-grafted DNA, and its use as a molecular building block that exploits its unique properties as a directional (poly)anion that exhibits molecular recognition. The selected examples highlight innovative applications of DNA at surfaces and interfaces ranging from molecular diagnostics and sequencing to biosensing.

Graphical abstract: “Smart” DNA interfaces

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Article information

DOI
https://doi.org/10.1039/C3CS60331H
Article type
Review Article
Submitted
18 Sep 2013
First published
18 Dec 2013

Chem. Soc. Rev., 2014,43, 1612-1626

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“Smart” DNA interfaces

V. Tjong, L. Tang, S. Zauscher and A. Chilkoti, Chem. Soc. Rev., 2014, 43, 1612 DOI: 10.1039/C3CS60331H

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