Recent progress in copper-catalyzed electrophilic amination

Abstract

Copper-catalyzed coupling reactions have been recognized as one of the most useful strategies for the formation of C–N bonds. This perspective gives an overview of the recent developments in copper-catalyzed electrophilic amination for the construction of various amines and their derivatives, including the electrophilic amination of various organometallic reagents and direct C–H bonds as well as the annulative electrophilic amination of o-alkynylphenols and o-alkynylanilines.