Issue 10, 2014

Towards a facile and convenient synthesis of highly functionalized indole derivatives based on multi-component reactions

Abstract

A library of potentially bioactive compounds through the novel 1H-indole-methyl-isocyanide and MCRs has been described. A flexible and efficient synthesis affording great complexity and diversity is achieved with moderate to good yields with no need for protection and deprotection steps.

Graphical abstract: Towards a facile and convenient synthesis of highly functionalized indole derivatives based on multi-component reactions

Supplementary files

Article information

Article type
Paper
Submitted
21 Jan 2014
Accepted
23 Jan 2014
First published
24 Jan 2014

Org. Biomol. Chem., 2014,12, 1649-1651

Author version available

Towards a facile and convenient synthesis of highly functionalized indole derivatives based on multi-component reactions

C. G. Neochoritis and A. Dömling, Org. Biomol. Chem., 2014, 12, 1649 DOI: 10.1039/C4OB00166D

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