Issue 34, 2014

Copper catalyzed C–O bond formation via oxidative cross-coupling reaction of aldehydes and ethers

Abstract

A practical and efficient construction of C–O bonds via oxidative cross-coupling reaction of aldehydes and ethers has been realized under open air. When 2 mol% copper was used as the catalyst, various α-acyloxy ethers were obtained with up to 93% isolated yield.

Graphical abstract: Copper catalyzed C–O bond formation via oxidative cross-coupling reaction of aldehydes and ethers

Supplementary files

Article information

Article type
Communication
Submitted
27 Apr 2014
Accepted
17 Jun 2014
First published
18 Jun 2014

Org. Biomol. Chem., 2014,12, 6549-6553

Author version available

Copper catalyzed C–O bond formation via oxidative cross-coupling reaction of aldehydes and ethers

Q. Wang, H. Zheng, W. Chai, D. Chen, X. Zeng, R. Fu and R. Yuan, Org. Biomol. Chem., 2014, 12, 6549 DOI: 10.1039/C4OB00862F

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