N-Methyliminodiacetic acid (MIDA) as a simple, air stable and water-soluble ligand has been used in the palladium-catalyzed Hiyama cross-coupling reaction of trimethoxyphenylsilane with aryl halides. The yield of the corresponding Hiyama coupling products is high up to around 90% in water and isopropanol under an ambient atmosphere in the presence of KOH and NaF.
M. Guo, L. Qi, Q. Zhang, Z. Zhu, W. Li and X. Li, Org. Biomol. Chem., 2014, 12, 7136 DOI: 10.1039/C4OB01056F
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