Issue 38, 2014

Palladium-catalyzed ortho-acylation of 2-benzyl-1,2,3-triazoles with aldehydes

Abstract

A palladium-catalyzed ortho-acylation of 2-benzyl-1,2,3-triazoles with aldehydes as an acyl source was developed. A wide variety of ketones containing 1,2,3-triazoles were obtained in good to excellent yields. This methodology provides a convenient access to the acylation of 2-substituted-1,2,3-triazoles.

Graphical abstract: Palladium-catalyzed ortho-acylation of 2-benzyl-1,2,3-triazoles with aldehydes

Supplementary files

Article information

Article type
Communication
Submitted
07 Jul 2014
Accepted
12 Aug 2014
First published
13 Aug 2014

Org. Biomol. Chem., 2014,12, 7474-7477

Palladium-catalyzed ortho-acylation of 2-benzyl-1,2,3-triazoles with aldehydes

Q. Tian, P. He and C. Kuang, Org. Biomol. Chem., 2014, 12, 7474 DOI: 10.1039/C4OB01406E

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