Issue 40, 2014
From the journal:

Organic & Biomolecular Chemistry

Synthesis of phenanthridine derivatives via cascade annulation of diaryliodonium salts and nitriles †

Jian Li,*ab   Hongni Wang,ab   Jiangtao Sun,ab   Yang Yangc  and  Li Liuc  

* Corresponding authors

a School of Pharmaceutical Engineering & Life Sciences, Chang Zhou University, Changzhou, P. R. China

b Key Laboratory of Advanced Catalytic Materials and Technology, Chang Zhou University, Changzhou, P. R. China

c School of Petrochemical Engineering, Chang Zhou University, Changzhou, P. R. China
E-mail: lijianchem@gmail.com
Fax: +86 519 86330224

Abstract

A cascade coupling reaction toward a variety of phenanthridine derivatives has been developed. This cascade transformation proceeds via the copper-catalyzed coupling reaction of diaryliodonium salts and nitriles, and undergoes cyclization into the phenanthridine core.

Graphical abstract: Synthesis of phenanthridine derivatives via cascade annulation of diaryliodonium salts and nitriles

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Article information

DOI
https://doi.org/10.1039/C4OB01504E
Article type
Communication
Submitted
17 Jul 2014
Accepted
28 Aug 2014
First published
28 Aug 2014

Org. Biomol. Chem., 2014,12, 7904-7908

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Synthesis of phenanthridine derivatives via cascade annulation of diaryliodonium salts and nitriles

J. Li, H. Wang, J. Sun, Y. Yang and L. Liu, Org. Biomol. Chem., 2014, 12, 7904 DOI: 10.1039/C4OB01504E

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