Issue 46, 2014
From the journal:

Organic & Biomolecular Chemistry

Solution structure of a cucurbit[8]uril induced compact supramolecular protein dimer†

Dung T. Dang,a   Ralph P. G. Bosmans,a   Christian Moitzi,b   Ilja K. Voetsc  and  Luc Brunsveld*ac  

* Corresponding authors

a Department of Biomedical Engineering, Eindhoven University of Technology, Den Dolech 2, Eindhoven, The Netherlands
E-mail: l.brunsveld@tue.nl
Fax: (+31)402478367

b Research & Development Particle Characterization, Anton Paar GmbH, Anton-Paar-Str. 20, A-8054 Graz, Austria

c Institute for Complex Molecular Systems, Eindhoven University of Technology, Den Dolech 2, Eindhoven, The Netherlands

Abstract

Supramolecular assembly of a beta-barrel protein via cucurbit[8]uril results in compact z-shaped protein dimers. SAXS data reveal the formation of a well ordered protein dimer, notwithstanding being connected by a reversible and flexible peptide linker, and highlight the supramolecular induced interplay of the proteins, analogous to covalently linked proteins.

Graphical abstract: Solution structure of a cucurbit[8]uril induced compact supramolecular protein dimer

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4OB01729C
Article type
Communication
Submitted
13 Aug 2014
Accepted
14 Oct 2014
First published
14 Oct 2014

Org. Biomol. Chem., 2014,12, 9341-9344

Author version available

Download author version (PDF)

Permissions

Request permissions

Solution structure of a cucurbit[8]uril induced compact supramolecular protein dimer

D. T. Dang, R. P. G. Bosmans, C. Moitzi, I. K. Voets and L. Brunsveld, Org. Biomol. Chem., 2014, 12, 9341 DOI: 10.1039/C4OB01729C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements