Silver-decorated biodegradable polymer vesicles with excellent antibacterial efficacy

Abstract

We report the first enzymatically degradable polymer vesicle decorated with silver nanoparticles, which showed low cytotoxicity against human normal liver L02 cells near the minimum inhibitory concentrations (MICs) but excellent antibacterial efficacy against both Gram-negative and Gram-positive bacteria with quite low MICs of 3.56 μg mL⁻¹ and 7.12 μg mL⁻¹, respectively, exhibiting promising potential applications in nanomedicine.