Issue 4, 2014

Palladium-catalyzed direct ortho-C–H ethoxycarboxylation of anilides at room temperature

Abstract

A Pd-catalyzed direct ortho-C–H ethoxycarboxylation of anilides has been established to form various anthranilic acid derivatives at room temperature. This protocol provides a concise and efficient strategy for diversifying the preparation of anthranilic acid derivatives from readily available starting materials under mild conditions.

Graphical abstract: Palladium-catalyzed direct ortho-C–H ethoxycarboxylation of anilides at room temperature

Supplementary files

Article information

Article type
Research Article
Submitted
15 Dec 2013
Accepted
26 Jan 2014
First published
11 Mar 2014

Org. Chem. Front., 2014,1, 347-350

Palladium-catalyzed direct ortho-C–H ethoxycarboxylation of anilides at room temperature

Y. Huang, G. Li, J. Huang and J. You, Org. Chem. Front., 2014, 1, 347 DOI: 10.1039/C3QO00069A

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