NBS-promoted halosulfonylation of terminal alkynes: highly regio- and stereoselective synthesis of (E)-β-halo vinylsulfones†
Abstract
An efficient NBS-promoted method for the synthesis of (E)-β-halo vinylsulfones has been developed. The present protocol went through an environmentally friendly metal-free process to achieve the halosulfonylation of terminal alkynes with high selectivity.