Issue 65, 2014
From the journal:

RSC Advances

Easy access for the synthesis of 2-aryl 2,3-dihydroquinazolin-4(1H)-ones using gem-dibromomethylarenes as synthetic aldehyde equivalent†

Kereyagalahally H. Narasimhamurthy,a   Siddappa Chandrappa,a   Kothanahally S. Sharath Kumar,a   Kachigere B. Harsha,a   Hanumappa Anandaa  and  Kanchugarakoppal S. Rangappa*a  

* Corresponding authors

a Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570006, India
E-mail: rangappaks@gmail.com, rangappaks@chemistry.uni-mysore.ac.in
Fax: +91-821-2412191
Tel: +91-821-2419661

Abstract

One step synthesis of 2,3-dihydroquinazolin-4(1H)-ones from gem-dibromomethylarenes using 2-aminobenzamide is described. Gem-dibromomethylarenes are used as aldehyde equivalent for the efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones, this synthesis takes shorter reaction time with quick isolation and excellent product yield.

Graphical abstract: Easy access for the synthesis of 2-aryl 2,3-dihydroquinazolin-4(1H)-ones using gem-dibromomethylarenes as synthetic aldehyde equivalent

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Article information

DOI
https://doi.org/10.1039/C4RA02312A
Article type
Paper
Submitted
17 Mar 2014
Accepted
17 Jul 2014
First published
22 Jul 2014

RSC Adv., 2014,4, 34479-34486

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Easy access for the synthesis of 2-aryl 2,3-dihydroquinazolin-4(1H)-ones using gem-dibromomethylarenes as synthetic aldehyde equivalent

K. H. Narasimhamurthy, S. Chandrappa, K. S. Sharath Kumar, K. B. Harsha, H. Ananda and K. S. Rangappa, RSC Adv., 2014, 4, 34479 DOI: 10.1039/C4RA02312A

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