Issue 49, 2014
From the journal:

RSC Advances

Enzyme catalytic promiscuity: lipase catalyzed synthesis of substituted 2H-chromenes by a three-component reaction†

Fengjuan Yang,‡ab   Zhi Wang,‡ab   Haoran Wang,ab   Hong Zhang,ac   Hong Yueab  and  Lei Wang*ab  

* Corresponding authors

a Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, Jilin University, Changchun 130023, P R China
E-mail: w_lei@jlu.edu.cn

b College of Life Science, Jilin University, Changchun 130023, P R China

c College of Chemistry, Jilin University, Changchun 130023, P R China

Abstract

A new method for the synthesis of substituted 2H-chromenes catalyzed by lipase was reported in the first time. Besides providing a simple and efficient method for the synthesis of 2H-chromenes, this study extends the applicability of lipase in organic synthesis.

Graphical abstract: Enzyme catalytic promiscuity: lipase catalyzed synthesis of substituted 2H-chromenes by a three-component reaction

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Article information

DOI
https://doi.org/10.1039/C4RA03367A
Article type
Communication
Submitted
14 Apr 2014
Accepted
30 May 2014
First published
03 Jun 2014

RSC Adv., 2014,4, 25633-25636

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Enzyme catalytic promiscuity: lipase catalyzed synthesis of substituted 2H-chromenes by a three-component reaction

F. Yang, Z. Wang, H. Wang, H. Zhang, H. Yue and L. Wang, RSC Adv., 2014, 4, 25633 DOI: 10.1039/C4RA03367A

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