A facile and practical one-pot synthesis of [1,2,4]triazolo[4,3-a]pyridines†
Abstract
A mild, efficient and operationally simple one-pot synthesis of substituted [1,2,4]triazolo[4,3-a]pyridines at room temperature from easily available 2-hydrazinopyridine and substituted aromatic aldehydes has been developed. This functional group tolerant and atom-economic method provides facile access to synthetically and biologically important triazolopyridine derivatives.