Issue 66, 2014

Metal-free sequential reaction via a propargylation, annulation and isomerization sequence for the one-pot synthesis of 2,3-disubstituted benzofurans

Abstract

A metal-free one-pot synthesis of 2,3-disubstituted benzofurans is described, which allows for the reactions to be performed under ambient conditions with readily accessible propargyl alcohols and general phenols, including phenols substituted with an electron withdrawing group or a nitrogen-containing group.

Graphical abstract: Metal-free sequential reaction via a propargylation, annulation and isomerization sequence for the one-pot synthesis of 2,3-disubstituted benzofurans

Supplementary files

Article information

Article type
Communication
Submitted
09 Jun 2014
Accepted
28 Jul 2014
First published
28 Jul 2014

RSC Adv., 2014,4, 34774-34779

Metal-free sequential reaction via a propargylation, annulation and isomerization sequence for the one-pot synthesis of 2,3-disubstituted benzofurans

W. Li, W. Nan and Q. Luo, RSC Adv., 2014, 4, 34774 DOI: 10.1039/C4RA05503A

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