A straight forward synthesis of 4-aryl substituted 2-quinolones via Heck reaction†
Abstract
A variety of aryl halides have been successfully coupled with different olefins via Heck reaction in the presence of an active stimulant (Pd–NHC). An efficient one pot protocol for the easy access of structurally diverse 4-aryl-2-quinolones via domino Heck/cyclization reaction has been developed.