Threading different metal nanomaterials on natural PhiX174 DNA to assemble a necklace

Abstract

Multiple nanomaterials were assembled on a circular DNA to form a necklace. AuNPs were first attached to natural PhiX174 ss-DNA, and then a single-circle PCR was adopted to immobilize the attachments. The structures of the assemblies were confirmed by TEM imaging and UV-vis spectrometry. In this way, various types and shapes of nanomaterials were assembled on the DNA, such as palladium nanocubes and gold nanorods.