Issue 90, 2014
From the journal:

RSC Advances

Rh(iii)-catalyzed annulation of N-methoxybenzamides with ynesulfonamides at room temperature: a practical and efficient route to 4-aminoisoquinolone derivatives†

Guangying Tan,‡a   Xiaolei Huang,‡a   Qian Wu,a   Luo-Qiang Zhanga  and  Jingsong You*a  

* Corresponding authors

a Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, 29 Wangjiang Road, Chengdu 610064, P. R. China
E-mail: jsyou@scu.edu.cn
Fax: +86-28-85412203

Abstract

A practical and efficient Rh(III)-catalyzed annulation of N-methoxybenzamides with ynesulfonamides for the synthesis of 4-aminoisoquinolone derivatives has been developed under external-oxidant-free conditions at room temperature. This protocol features good functional group tolerance and excellent selectivity.

Graphical abstract: Rh(iii)-catalyzed annulation of N-methoxybenzamides with ynesulfonamides at room temperature: a practical and efficient route to 4-aminoisoquinolone derivatives

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Article information

DOI
https://doi.org/10.1039/C4RA09500F
Article type
Communication
Submitted
02 Aug 2014
Accepted
16 Sep 2014
First published
19 Sep 2014

RSC Adv., 2014,4, 49186-49189

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Rh(III)-catalyzed annulation of N-methoxybenzamides with ynesulfonamides at room temperature: a practical and efficient route to 4-aminoisoquinolone derivatives

G. Tan, X. Huang, Q. Wu, L. Zhang and J. You, RSC Adv., 2014, 4, 49186 DOI: 10.1039/C4RA09500F

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