SERS-active Ag@Au core–shell NP assemblies for DNA detection

Yuan Zhao; Liqiang Liu; Hua Kuang; Libing Wang; Chuanlai Xu

doi:10.1039/C4RA11112E

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SERS-active Ag@Au core–shell NP assemblies for DNA detection†

Yuan Zhao,^ab Liqiang Liu,

^a Hua Kuang,*^a Libing Wang^a and Chuanlai Xu^a

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* Corresponding authors

^a State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, People's Republic of China
E-mail: kuangh@jiangnan.edu.cn

^b The Key Lab of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Materials Engineering, Jiangnan University, Wuxi, Jiangsu, People's Republic of China

Abstract

An innovative Raman sensor was developed for DNA detection, based on silver@gold (Ag@Au) core–shell nanoparticle (NP) assemblies fabricated by a polymerase chain reaction (PCR). The combination of exponential amplification by PCR and the amplified Raman signal achieved DNA detection of 11.8 aM.

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Article information

DOI: https://doi.org/10.1039/C4RA11112E
Article type: Communication
Submitted: 26 Sep 2014
Accepted: 22 Oct 2014
First published: 22 Oct 2014

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RSC Adv., 2014,4, 56052-56056

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SERS-active Ag@Au core–shell NP assemblies for DNA detection

Y. Zhao, L. Liu, H. Kuang, L. Wang and C. Xu, RSC Adv., 2014, 4, 56052 DOI: 10.1039/C4RA11112E

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SERS-active Ag@Au core–shell NP assemblies for DNA detection†

Abstract

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SERS-active Ag@Au core–shell NP assemblies for DNA detection

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