Issue 21, 2014

Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy

Abstract

The gene transfection efficiency of Au@PDMS–PLL soft nanocomposites was higher than those of SiO2–PLL and PEI; and moreover, the nanocomposites did not show significant cell cytotoxicity in in vitro measurements. The soft nanocomposites were also sensitive during photothermal therapy with infrared light, which produced a cytotoxic effect on the targeted HeLa cells.

Graphical abstract: Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy

Supplementary files

Article information

Article type
Communication
Submitted
19 Feb 2014
Accepted
16 Mar 2014
First published
18 Mar 2014

J. Mater. Chem. B, 2014,2, 3185-3189

Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy

J. H. Byeon and Y. Kim, J. Mater. Chem. B, 2014, 2, 3185 DOI: 10.1039/C4TB00271G

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