Issue 6, 2015
From the journal:

Analyst

Monodispersed nanoparticles of conjugated polyelectrolyte brush with high charge density for rapid, specific and label-free detection of tumor marker†

Xingfen Liu,a   Lin Shi,a   Zhiyong Zhang,a   Quli Fan,*a   Yanqin Huang,a   Shao Su,a   Chunhai Fan,*b   Lianhui Wanga  and  Wei Huang*ac  

* Corresponding authors

a Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing University of Posts and Telecommunications, Nanjing 210023, China
E-mail: iamqlfan@njupt.edu.cn, iamwhuang@njtech.edu.cn

b Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
E-mail: fchh@sinap.ac.cn

c Key Laboratory of Flexible Electronics & Institute of Advanced Materials, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing Tech University (Nanjing Tech), Nanjing 211816, China

Abstract

Highly charged nanoparticles of a conjugated polyelectrolyte brush were used to sense the human α-fetoprotein (AFP) by observing selective superquenching in several minutes. The unique property of nanoparticles that the self-aggregation causes an unchanged or enhanced fluorescence can reduce the interference from non-target substance significantly.

Graphical abstract: Monodispersed nanoparticles of conjugated polyelectrolyte brush with high charge density for rapid, specific and label-free detection of tumor marker

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Article information

DOI
https://doi.org/10.1039/C4AN02384F
Article type
Communication
Submitted
27 Dec 2014
Accepted
05 Feb 2015
First published
05 Feb 2015

Analyst, 2015,140, 1842-1846

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Monodispersed nanoparticles of conjugated polyelectrolyte brush with high charge density for rapid, specific and label-free detection of tumor marker

X. Liu, L. Shi, Z. Zhang, Q. Fan, Y. Huang, S. Su, C. Fan, L. Wang and W. Huang, Analyst, 2015, 140, 1842 DOI: 10.1039/C4AN02384F

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