Issue 16, 2015
From the journal:

Analyst

Label-free fluorescence light-up detection of T4 polynucleotide kinase activity using the split-to-intact G-quadruplex strategy by ligation-triggered and toehold-mediated strand displacement release†

Lu Zhou,‡a   Xiaoqiang Shen,‡a   Na Sun,a   Kewei Wang,a   Yuanyuan Zhanga  and  Renjun Pei*a  

* Corresponding authors

a Key Laboratory of Nano-Bio Interfacce, Division of Nanobiomedicine, Suzhou Insitute of Nano-Tech and Nano-Bionics, Chinese Academy of Science, Suzhou, China
E-mail: rjpei2011@sinano.ac.cn

Abstract

A label-free, fluorescence light-up detection method for T4 polynucleotide kinase activity has been developed using the split-to-intact G-quadruplex strategy.

Graphical abstract: Label-free fluorescence light-up detection of T4 polynucleotide kinase activity using the split-to-intact G-quadruplex strategy by ligation-triggered and toehold-mediated strand displacement release

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Article information

DOI
https://doi.org/10.1039/C5AN01032B
Article type
Communication
Submitted
22 May 2015
Accepted
09 Jun 2015
First published
09 Jun 2015

Analyst, 2015,140, 5450-5453

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Label-free fluorescence light-up detection of T4 polynucleotide kinase activity using the split-to-intact G-quadruplex strategy by ligation-triggered and toehold-mediated strand displacement release

L. Zhou, X. Shen, N. Sun, K. Wang, Y. Zhang and R. Pei, Analyst, 2015, 140, 5450 DOI: 10.1039/C5AN01032B

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