Activation of Mg2+-dependent DNAzymes based on AP site-containing triplex for specific melamine recognition

Ya Wang; Junying Zhang; Linling Zhu; Linlin Lu; Chongchong Feng; Fengyang Wang; Zhiai Xu; Wen Zhang

doi:10.1039/C5AN01515D

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Activation of Mg²⁺-dependent DNAzymes based on AP site-containing triplex for specific melamine recognition†

Ya Wang,^a Junying Zhang,^a Linling Zhu,^a Linlin Lu,^a Chongchong Feng,^a Fengyang Wang,^a Zhiai Xu*^a and Wen Zhang*^a

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* Corresponding authors

^a School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, P.R. China
E-mail: zaxu@chem.ecnu.edu.cn, wzhang@chem.ecnu.edu.cn

Abstract

Based on melamine binding-triggered triplex formation and subsequent activation of Mg²⁺-dependent DNAzymes, a novel strategy for DNAzyme regulation was proposed and developed for melamine recognition.

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Article information

DOI: https://doi.org/10.1039/C5AN01515D
Article type: Communication
Submitted: 25 Jul 2015
Accepted: 27 Sep 2015
First published: 09 Oct 2015

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Analyst, 2015,140, 7508-7512

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Activation of Mg²⁺-dependent DNAzymes based on AP site-containing triplex for specific melamine recognition

Y. Wang, J. Zhang, L. Zhu, L. Lu, C. Feng, F. Wang, Z. Xu and W. Zhang, Analyst, 2015, 140, 7508 DOI: 10.1039/C5AN01515D

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