Using silica coated magnetite nanoparticles modified with anionic surfactant aggregates as a solid phase microextraction adsorbent for determination of fluoroquinolones in egg samples by spectrofluorimetry

Abstract

We developed a simple microextraction method for extraction and pre-concentration of trace amounts of fluoroquinolones as polar model drugs in egg samples using an ionic surfactant. The present method, based on the use of silica–magnetite nanoparticles modified with anionic surfactant aggregates, was applied for determination of fluoroquinolones. The target analytes were converted into their ion pair complexes with dodecyl benzene sulphonic acid sodium (SDBS) and then extracted into an organic solvent. The factors influencing the extraction were investigated and optimized. Under optimum extraction conditions, a limit of detection (LOD) as small as 0.0029 mg L⁻¹ and a linear dynamic range of 0.0083–0.166 mg L⁻¹ were obtained for enrofloxacin in egg samples. The obtained results indicate that the proposed method is efficient, fast and inexpensive for extraction and determination of fluoroquinolones in real samples.